An association study between catechol-O-methyl transferase gene polymorphism and methamphetamine psychotic disorder: Psychiatric Genetics Vol 16(4) Aug 2006, 133-138. (2005). It also occurs naturally in some food. Is COMT a susceptibility gene for schizophrenia? Craddock, N., Owen, M. J., & O'Donovan, M. C. (2006). Farmer, A., Elkin, A., & McGuffin, P. (2007). COMT inhibitors, like entacapone saves L-dopa from COMT and prolongs the action of L-dopa. Effects of stress on catecholamine stores in central and peripheral tissues of long-term socially isolated rats: Brazilian Journal of Medical and Biological Research Vol 39(6) Jun 2006, 785-790. While catechol is found naturally in some foods, there is no evidence to show that the natural presence of catechol in food poses a health risk to Canadians or that Canadians should avoid foods containing catechol. Schott, B. H., Seidenbecher, C. I., Fenker, D. B., Lauer, C. J., Bunzeck, N., Bernstein, H.-G., et al. Palmatier, M. A., Pakstis, A. J., Speed, W., Paschou, P., Goldman, D., Odunsi, A., et al. Catechol is used as a component in photographic developer and in specific applications such as a laboratory reagent and an antioxidant in electroplating baths. What is catechol and where in nature is it found? Joo, E.-J., Jeong, S.-H., Ahn, Y.-M., Lee, K.-Y., Yoon, S. C., Kim, E.-J., et al. Jabbi, M., Korf, J., Kema, I. P., Hartman, C., van der Pompe, G., Minderaa, R. B., et al. The O in the name stands for oxygen, not for ortho. Exploring joint effects of genes and the clinical efficacy of morphine for cancer pain: OPRM1 and COMT gene: Pain Vol 130(1-2) Jul 2007, 25-30. How much will a midwifery schooling cost? Association between a catechol-o-methyltransferase polymorphism and obsessive-compulsive disorder in the Afrikaner population: Journal of Affective Disorders Vol 65(1) Jun 2001, 61-65. A., Galke, B. L., Wolyniec, P. S., Nestadt, G., Antonarakis, S. E., et al. Why don't libraries smell like bookstores? COMT haplotypes suggest P2 promoter region relevance for schizophrenia: Molecular Psychiatry Vol 9(9) Sep 2004, 859-870. An association study between 5-HTTLPR polymorphism, COMT polymorphism, and Tourette's syndrome: Psychiatry Research Vol 97(2-3) Dec 2000, 93-100. The industrial uses of catechol do not result in exposure to the general population. A catecholamine is a monoamine, an organic compound that has a How long will the footprints on the moon last? Catechol is the key molecule found in the byssus of mussel adhesive proteins (MAPs) secreted by the mussel’s foot and responsible for the great adherence to rocks in wet conditions [50,51]. Based on the most recent data, catechol is manufactured in Canada and is imported into Canada. COMT Valsuperscript 1-sup-5-sup-8 Met and BDNF Csuperscript 2-sup-7-sup-0T polymorphisms in schizophrenia: A case-control study: Schizophrenia Research Vol 73(1) Feb 2005, 27-30. Identification of sequence variants and analysis of the role of the catechol-O-methyl-transferase gene in schizophrenia susceptibility: Biological Psychiatry Vol 43(6) Mar 1998, 425-431. Gene-gene interaction between MAOA and COMT in suicidal behavior: Analysis in schizophrenia: Brain Research Vol 1097(1) Jun 2006, 26-30. Catechol is a chemical, but It has been shown that this valine variant catabolizes dopamine at up to four times the rate of its methionine counterpart, resulting in a significant reduction of synaptic dopamine following neurotransmitter release, ultimately reducing dopaminergic stimulation of the post-synaptic neuron.

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